Clinical Engagement Lead - West / Midwest

About Beeline Medicines: Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune-mediated diseases can live life fully. Job Summary: The Clinical Engagement Lead, US is a field-based is a senior level, site facing clinical development professional responsible for building and managing investigator and site relationships across the globe in support of the organization's clinical trial portfolio. This role serves as the primary site-facing liaison between the organization and its global clinical investigators, academic medical centers, and research sites — supporting site identification, investigator engagement, and clinical trial execution to position the organization’s I&I programs competitively in the clinical research landscape. The Clinical Engagement Lead combines knowledge of the I&I therapeutic area with strong relationship management skills and a thorough understanding of clinical trial operations — serving as a trusted partner to investigators and a critical field intelligence link back to the internal Clinical Development and Medical Affairs teams. This is a highly visible, externally focused role that requires the ability to represent the organization’s science with authority, build lasting relationships with leading clinical researchers, and operate independently across a broad assigned geography. Work Arrangement & Location: Field-Based - This position is field-based, and the incumbent will be expected to work within their assigned territory or region on behalf of the company. Regular travel within the designated geography is an inherent requirement of this role. Additional travel outside of the assigned territory may be required based on business need, including attendance at company meetings, training, or other organizational events. Territory Assignment Notice: AK, AZ, CA, CO, HI, ID, IA, IL, KS, MN, MT, ND, NE, NV, OR, SD, UT, WA, WI, WY Notice: The geographic territory outlined for this position reflects current business needs and is subject to change at the discretion of the organization. Territory boundaries, state assignments, and regional alignments may be modified at any time based on evolving business priorities, organizational restructuring, or strategic initiatives. The selected candidate will be expected to adapt to any such changes as a condition of employment. Essential Duties and Responsibilities: • Build and manage a portfolio of region/country investigator and clinical site relationships in the I&I therapeutic area — identifying, engaging, and developing long-term partnerships with principal investigators, academic medical centers, community research sites, and subspecialty practices relevant to Beeline's clinical programs. • Lead site identification and feasibility activities for clinical trials — conducting operational site assessments, evaluating investigator interest and patient population access, and providing strategic recommendations to Clinical Development and Clinical Operations on site selection and activation. • Serve as the primary clinical liaison to regional/country level investigators — facilitating peer-to-peer scientific exchange on Beeline's pipeline, conducting protocol discussions, supporting site initiation and training, and maintaining ongoing engagement with investigators throughout the trial lifecycle. • Support clinical trial enrollment and retention at region/country sites — working proactively with investigators and site staff to identify enrollment challenges, implement site-level solutions, and maintain site motivation and engagement across all active Beeline studies. • Capture and communicate region/country clinical landscape intelligence — including investigator perspectives, competitive trial activity, site capacity trends, and unmet medical need insights — back to Clinical Development, Medical Affairs, and Commercial teams in a structured, actionable manner. • Partner with Medical Affairs MSLs to ensure coordination and alignment of scientific engagement activities at the investigator level — establishing clear boundaries between clinical trial support and medical affairs activities and collaborating to maximize the impact of both. • Represent organization clinical and scientific meetings, investigator symposia, disease-area conferences, and site visits — engaging with the clinical research community as a credible, knowledgeable, and trusted organizational representative. • Develop and implement site engagement strategies to improve study start-up, enrollment performance, retention, and site satisfaction. • Partner closely with investigators, study coordinators, and site staff to support patient identification and recruitment efforts. • Provide operational guidance and best practices to sites related to diverse patient enrollment and community engagement. • Conduct regular field engagement with investigative sites and community stakeholders to strengthen study execution and recruitment performance. • Monitor enrollment trends, site performance metrics, and patient engagement effectiveness using data-driven approaches. • Identify enrollment risks proactively and implement mitigation and recovery plans. • Perform other duties and responsibilities as assigned. Qualifications: • Education: Bachelors degree in scientific or related discipline required. Advanced degree preferred—MS or MPH in a relevant clinical, biomedical, or pharmaceutical sciences discipline. • 8+ years of experience in clinical development, clinical research, clinical operations, or a field-based clinical engagement role within the pharmaceutical or biotech industry. • Demonstrated experience managing investigator relationships and supporting clinical trial site activation and enrollment. • Experience in immunology, inflammation, or a related therapeutic area strongly preferred. • Experience collaborating with CROs, investigative sites, and field medical teams, including MSL partnerships. • Strong scientific and clinical knowledge of immunology and inflammation — including disease biology, standard of care, clinical trial design considerations, and the competitive clinical research landscape across relevant I&I indications. • Expertise in clinical trial site management and investigator engagement — including site feasibility assessment, investigator identification and qualification, site initiation support, and enrollment optimization strategies. • Working knowledge of GCP requirements, ICH guidelines, and FDA regulations governing investigator interactions, clinical site oversight, and field-based clinical development activities. • Highly self-directed field professional — manages a complex investigator portfolio independently, prioritizes site engagement activities strategically, and operates with minimal supervision across a broad geography. • Relationship-driven and trusted clinical trial resource — builds genuine, long-term partnerships with investigators and site staff based on scientific credibility, reliability, and authentic commitment to supporting research excellence. • Proactive field intelligence contributor — consistently translates field observations into actionable insights that improve program strategy, site selection, and enrollment performance. • Ability to safely and successfully operate a motor vehicle is required. Valid US Driver’s License and a driving record in compliance with company standards • Position may require ability to travel 50%+ as needed of time or more including occasional overnight stay driven by business need. • Must be able to work evenings and weekends, as needed, for physician or patient events (both in person and virtual). • Depending on geography, must have the ability to manage a multi-state territory with diverse customer base. Salary Range: The expected salary range for this position varies by location and will be communicated based on the country or region in which the selected candidate is hired. Actual pay will be determined based on experience, qualifications, location, and other job-related factors permitted by applicable local law. A discretionary annual bonus and long-term incentive award (e.g., equity) may be available based on individual and Company performance. Salary Range $180,000—$235,000 USD Benefits: We offer a comprehensive benefits package tailored to the country and region in which you are hired, in compliance with local laws and practices. Benefits may include, but are not limited to: • Competitive health and wellness coverage (structure and premiums vary by country) • Paid time off, public holidays, and additional leave entitlements in accordance with local requirements • Flexible work arrangements / hybrid schedule Benefits vary by location and are subject to eligibility requirements, local regulations, and plan terms. Specific benefit details applicable to your country or region will be provided during the offer process. Equal Employment Opportunity: Beeline Medicines is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability, age, protected veteran status, or any other characteristic protected by applicable federal, state, or local law. Reasonable Accommodation: If you require a reasonable accommodation to participate in the application or interview process, please contact careers@beelinemedicines.com to request an accommodation. We are committed to providing equal access to all candidates. Privacy Upon submission of this form I understand that Beeline Medicines is based in the United States and personal data submitted in the form will be transferred and accessed in the U.S., Information about Beeline Medicines privacy practices can be found at Privacy Policy - Beeline Medicines